Mathematical theory of population genetics, fall 2012
Mathematical theory of population genetics, fall 2012
Population genetics studies the genetic composition of biological populations, and its change under the influence of various factors, including natural selection, mutation, recombination and migration. Population genetics thus provides the basis for understanding the evolutionary processes that have led to the biodiversity we encounter today.
In this course we get familiar with focal concepts and build a theoretical framework to gain proper understanding of the relevant evolutionary processes. Course will cover elementary population genetics (e.g. Hardy-Weinberg law, selection at single locus), mutation-selection models at two or more loci, equations for quantitative traits under selection and basic principles of coalescent theory.
Lecturer
Scope
10 cu.
Type
Advanced studies
Prerequisites
Basic knowledge of dynamical equations (discrete dynamical systems and differential equations) and probability theory.
Lectures
Weeks 36-42 and 44-50, Monday 14-16 in room C122 (note the change!) and Wednesday 14-16 in room B322. Two hours of exercise classes per week.
Note! Monday lecture 26.11 cancelled.
Exams
Date, time and place: 17.12.2012, 14.15 - 16.00, room C122.
Bibliography
Lecture notes will be mainly based on the book by Burger (2000): The mathematical theory of selection, recombination and mutation, and on the book by Wakeley (2009): Coalescent theory: an introduction.
Registration
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Exercise groups
Group | Day | Time | Place | Instructor |
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1. | Thursday | 10-12 | B321 | Tadeas Priklopil |
Feedback!
Below you will find a link to a feedback page, where you can express (anonymously) your thoughts about the course. In particular, it would be interesting to know whether some topics dealt in the course were too superficial/too detailed, or whether you have suggestions for future topics, or whether the course material should be improved (and if so, in which way), or etc.. ALL THE COMMENTS ARE WELCOME! Note, that you have a big influence on the content of the course, which will be given also in future semesters (those who give signed comments will be in the acknowledgments of the course material!).
Link to the feedback page (note that the textbox can be enlarged by dragging the bottom right corner)
Course material
week | topic | exercises | solutions |
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week 1 |
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| 5.9. Introductory lecture. |
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week 2 | 10.9. Hardy-Weinberg |
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| 12.9. Average effects |
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week 3 |
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week 4 | 24.9. Selection models - part I |
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| 26.9. Selection models - part II |
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week 5 | 1.10. Protected coexistence - part I |
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| 3.10. Protected coexistence - part II |
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Lecture notes Slides Exercises Solutions
5.9.2012 13.9.2012
10.9.2012 10.9.2012 27.9.2012 (corrected)
12.9.2012
24.-26.9.2012 26.9.2012 4.10.2012
1.10.-3.10.2012 3.10.2012 11.10.2012
8.10.-10.10.2012 (corrected) 18.10.2012 (corrected)
15.10-17.10.2012 17.10.2012 1.11.2012
29.10.-31.10.2012 8.11.2012
5.11.-7.11.2012 (corrected) 15.11.2012 (corrected)
12.11.-21.11 29.11.2012
28.11 - 3.11. Notes based on and
3.11-5.11 13.12.2012
Appendix I