Title: Non-Markovian Effects, Quantum Jumps and Fluctuation Relations in Driven Quantum Systems Abstract: Definition and measurement of work done on a driven open quantum system remain major challenges in quantum thermodynamics. The stochastic mapping of an open quantum system to the Lindblad master equation and its unraveling by quantum jumps offers a powerful way to define and calculate thermodynamics of work and the related fluctuation relations [1]. However, several approximations must be made including that of Markovianity of the dynamics. A calorimetric detection method has recently been proposed by J. Pekola and collaborators [2] as a feasible experimental scheme to measure work and fluctuation relations. However, the detection requires a finite size for the environment, which influences the system dynamics. This process cannot be modeled with the standard Markovian stochastic approaches. We develop a quantum jump model suitable for systems coupled to a finite-size environment and discuss its application to work measurement and fluctuation relations [3]. We also discuss the consequences of non-Markovianity in entropy production in strongly coupled systems [4]. 1. S. Suomela, J. Salmilehto, I.G. Savenko, T. Ala-Nissila, and M. Mottonen, Phys. Rev. E 91, 022126 (2016). 2. J.P. Pekola, P. Solinas, A. Shnirman, and D.V. Averin, New J. of Phys. 15, 115006 (2013). 3. S. Suomela, A. Kutvonen, and T. Ala-Nissila, Phys. Rev. E 93, 062106 (2016); S. Suomela, R. Sampaio, and T. Ala-Nissila, Phys. Rev. E 94, 032138; J.P. Pekola, S. Suomela and Y.M. Galperin, J. Low Temp. Phys. (2016). 4. A. Kutvonen, T. Ala-Nissila, and J. Pekola, Phys. Rev. E 92, 012107 (2015).