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Statistical methods in medicine and epidemiology, fall 2011

News

The last lecture is on Tuesday (December 13). We start in
the computer class at 3:15 p.m. (see an extra R exercise below;
we will do this partly). After the computer class, a wrap-up
session in B120.

Survival regression in R

The second course exam will be on Thursday, December 15. We will
start at 4 p.m. sharp. The exam ends at 7 p.m. The exam will cover
the 2nd part of the course (see below for a detailed list of topics).

Lecturer

Kari Auranen

Scope

6-10 cu.

Type

Advanced studies

Prerequisites

Lecture summaries

1. The binary model. Conditional probability. Bayes formula. (Chapters 1 and 2)
2. Likelihood function (Chapter 3)
3. Estimation of survival. The hazard function. (Chapters 4 and 5)
4. Time. Competing risks. Censoring. (Chapters 6 and 7)
5. Approximating likelihoods. Statistical paradigms. (Chapters 8, 9 and 10)

6. P values (Chapter 11)

7. P values continued

8. Estimation of relative rates (Chapter 13)

9. Confounding. Stratification. Standardisation (Chapter 14 aand 15)

10. The lecture on confounding continued.

11. Case-control studies (Chapter 16)

12. Lecture. The lecture on case-control studies continued.

13. Matching

14. Part I: Poisson regression

14. Part II: Logistic regression

15. Samplesize

16. Hypothesis testing. Interaction

17. Model choice

18. Cox regression

19. Two articles on p values and statistical evidence
http://www.rni.helsinki.fi/~kja/epid11/article2.pdf

Errata

Exercises

1. Exercise

Data file (atresia.dat) The data matrix has 4 columns: individual ID, age at diagnosis, age at death or censoring,
failure indicator (1=death/0=censoring)

2. Exercise

3. Exercise

4. Exercise

5. Exercise

6.Exercise

7. Exercise (R practical)

8. Exercise

9. Exercise (R practical)

Answers to Exercise 1

Answers to Exercise 2

Answers to exercise 3

Answers to exercise 4

Answers to exercise 5

Answers to exercise 6

Answers to exercise 8

Datasets

CHD.dat
BCG.dat
BCGcasecontrol.dat
BCGmatched.dat
doseresponse.dat

Exams

The first course exam is on October 18 (Tuesday) at 4-7 p.m. Please
note the date which has changed from Thursday (Oct 20) to Tuesday (Oct 18).

The second course exam is on December 15 (Thursday) at 4-7 p.m. The
exam covers lectures 12-19, exercise 6-9 and the following chapters
from the textbook:

Chapters 16, 17, 18 (except 18.2), 19, 21, 22, 23 (except 23.4),24, 25, 26,29, 30.

Bibliography

Registration

Did you forget to register? What to do.

Exercise groups

Group

Day

Time

Place

Instructor

1.

 

 

 

 

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