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• Statistical genetics, spring 2015
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# Statistical genetics, spring 2015

### Lecturer

Sirkka-Liisa Varvio

### Scope, type, prerequisites

5-10 cr, intermediate / advanced studies
If you have already taken this course, do not plan to take Statistical genetics spring 2015. Although the courses are not identical, there will be too much overlapping content in order to regard the credits as non-overlapping.

### Time schedule

III period (5 cr option),  Wednesday 14-18 (-20 if needed)  in computer class C128.

Passing the course and the grade

• Five assignments or assignment sets / home-exercise sets. These will be graded. There will not be an exam.
• You get 1 point from each assignment /assignment set  if your performance is excellent, 0.7-0.8 from good performance, 0.5 from moderate, and 0.2 from an acceptable performance.
• Final grade 5 comes from 4.2 assignment points and final grade 1 comes from 2.5 points.
• The other three assignments (tba, they will be data-analysis, getting familiar with scientific articles, etc.)
 Wed 21.1 The current mainstream of statistical genetics, see hereBasic concepts 1_Inheritance, probability, Hardy-Weinberg.pdf, assignment set 1 included, simulations: http://www.radford.edu/~rsheehy/Gen_flash/popgen/ Wed 28.2 Basic concepts 2_Selection, mutation, drift.pdf, assignment set 2 included Wed  4.2 Christian Benner from FIMM: Statistical_Concepts_In_A_Nutshell_Part1.pdf, Statistical_concepts_in_a_nutshell_Part2.pdf Wed (11.2),18.2,25.2 Assignments for 3 more credits (2cr come from assignment sets 1 and 2): You can choose, whether writing essays or doing data-analysis, or both. If you want to get the 5 cr before IV period, then you submit your work for 3 cr  8. March, at the latest. Then you can continue for more credits during period IV. In data-analysis assignments the definition 1-2 cr means that you can do a "small" work for 1 cr (to obtain the credits for the 5 cr option), and continue for a more comprehensive work later. However, you don´t have to do first 1 cr and then continue for the other credit, you can start by doing a 2 cr work.Assignment 3, 1-3 cr by writing essays. One essay, 1 cr, is about 5 pages text. Below are review-type recent scientific papers. For one essay, you pick one paper and find another paper by yourself (for example on the basis of the original paper´s reference list). The additional paper is a kind of specific example on the the general topic introduced in the original review-paper.Topics, the review-type scientific papers:Assignment 4.docx, 1-2 cr by analysing human population data:Assignment 5.pdf, Assignment 5 clarification.docx,  1-2 cr by analysing bacteria data:Assignment 6 , (TBA) , 1-2 cr by analysing virus datadata TBASoftware (installed in C128; you can also install these free programs to your own computer):

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