Genome-wide association studies, GWAS-minicourse, fall 2013
Samuli Ripatti and Matti Pirinen from FIMM
Faculty of Medicine master´s or PhD-students: questions in advance to samuli.ripatti at helsinki.fi and matti.pirinen at helsinki.fi
Questions in advance from other students (for example math-stat, comp sci, biosci): Sirkka-Liisa Varvio
Scope, type and prerequisites
2 cr, advanced/intermediate studies. Prerequisites: Statistics, R; take this course if you are not familiar with R: Statistical software tools I(-II).
Statistical genetics, concepts which are in the program of this course: Biometry and bioinformatics III
Lectures and computer class sessions
Tuesday 26.11, 14-16 in CK112
Tuesday 3.12, 14-16 in CK112, 16-18 in C128
Tuesday 10.12, 14-16 in CK112, 16-18 in C128
Short content description
Human Genetics and Biostatistics
Heritability - Linkage studies - Association studies - Genotyping technologies - Quality control
Statistics of association mapping (significance and power vs. priors and evidence)
Examples of real studies - Recent topics in GWAS world (e.g. missing heritability, synthetic associations,...)
Why do we think that certain phenotype has a genetic component?
How does gene mapping work with family data and how does it work with population data?
What kind of data modern genotyping technologies produce and how to analyse them?
What have we learned during the last five years from genome-wide association studies?
And what have we not learned so far?
26.11, 14-16, CK112 Samuli Ripatti lecture 26.11.2013.pdf
3.12 and 10.12, 14-16, CK112 and 16-18 C128 Lectures and practicals by Matti Pirinen, Material is here
Exam is based on the lectures, practicals and literature given in Matti Pirinen page ( Material is here , material marked as "extra" is NOT required for the exam) .
The questions for the exam are sent out 12. December and are to be returned 17. December.
BB III - Moodle
Use this registration if you take only the 2 cr GWAS-minicourse.
Do not use this registration if you take the whole Biometry and bioinformatics III course, of which GWAS-minicourse is one module. Your registration to BB III covers registration to GWAS.
Did you forget to register? What to do?